業績リスト

1. Comparative immunity of antigen recognition, differentiation and other functional molecules―similarities and differences among common marmoset, human and mouse.
Review Yoshie Kametani*, Takashi Shiina, Ryuji Suzuki, Erika Sasaki, Sonoko Habu Experimental Animals, in press

2. The response of common marmoset immunity against cedar pollen extract.
Kametani Y*, Yamada Y, Takabayashi S, Kato H, Ishiwata K, Watanabe N, Sasaki E, Habu S Bioscience trends, 2018 12(1):94-101

3. B cell populations are expanded in breast cancer patients compared with healthy controls.
Banri Tsuda, Asuka Miyamoto, Kozue Yokoyama, Rin Ogiya, Risa Nishino, Mayako Terao, Toru Morioka, Naoki Niikura, Takuho Okamura, Hirohito Miyako, Yuki Saito, Yasuhiro Suzuki, Yoshie Kameteni, Yutaka Tokuda Breast Cancer, in press doi: 10.1007/s12282-017-0824-6 

4. NOG-hIL-4-Tg, a new humanized mouse model for producing tumor antigen-specific IgG antibody by peptide vaccination.
Yoshie Kametani*, Ikumi Katano, Asuka Miyamoto, Yusuke Kikuchi, Ryoji Ito, Yukari Muguruma, Banri Tsuda, Sonoko Habu, Yutaka Tokuda, Kiyoshi Ando, Mamoru Ito PLOS ONE 2017 12(6):e0179239. doi: 10.1371/journal.pone.0179239

5. ヒト免疫系再構築NOGマウスの発展 宮本あすか,亀谷美恵 東海大学先進生命科学研究所紀要 2017 1:14-17

6. Production of a Locus and Allele-Specific Monoclonal Antibody for the Characterisation of SLA-1*0401 mRNA and Protein Expression Levels in MHC-Defined Microminipigs.
Yoshie Kametani*, Shino Ohshima, Asuka Miyamoto, Atsuko Shigenari, Masaki Takasu, Noriaki Imaeda, Tatsuya Matsubara, Masafumi Tanaka, Takashi Shiina, Hiroshi Kamiguchi, Ryuji Suzuki, Hitoshi Kitagawa, Jerzy K. Kulski, Noriaki Hirayama, Hidetoshi Inoko, Asako Ando PLOS ONE 2016 11(10):e0164995. doi: 10.1371/journal.pone.0164995.

7. Identification and characterization of two CD4 alleles in Microminipigs.
Tatsuya Matsubara, Naohito Nishii, Satoshi Takashima, Masaki Takasu, Noriaki Imaeda, Kayo Aiki-Oshimo, Kazuaki Yamazoe, Michinori Kakisaka, Shin-nosuke Takeshima, Yoko Aida, Yoshie Kametani, Jerzy K Kulski, Asako Ando, Hitoshi Kitagawa BMC Veterinary Research 2016 Oct 7;12(1):222.

8. ヒトにおける妊娠免疫 和泉俊一郎、近藤朱音、亀谷美恵 「ホルモンから見た生命現象と進化シリーズ」第7巻「生体防御・社会性 ?守?」p62-p75

9. Generation of a Nonhuman Primate Model of Severe Combined Immunodeficiency Using Highly Efficient Genome Editing.
Sato K, Oiwa R, Kumita W, Henry R, Sakuma T, Ito R, Nozu R, Inoue T, Katano I, Sato K, Okahara N, Okahara J, Shimizu Y, Yamamoto M, Hanazawa K, Kawakami T, Kametani Y, Suzuki R, Takahashi T, Weinstein EJ, Yamamoto T, Sakakibara Y, Habu S, Hata JI, Okano H, Sasaki E. Cell Stem Cell. 2016 19(1):127-138 doi: 10.1016/j.stem.2016.06.003. PMID: 27374787

10. Reduced Immunocompetent B Cells and Increased Secondary Infection in Elderly Patients with Severe Sepsis.
Suzuki K, Inoue S, Kametani Y, Komori Y, Chiba S, Sato T, Inokuchi S, Ogura S. Shock. 2016 46(3):270-8. doi: 10.1097/SHK.0000000000000619.

11. Antibody-secreting plasma cells with unique CD5+IgG+CD21lo phenotype developed in humanized NOG mice.
Yoshie Kametani*, Shin Shimada, Shuhya Mori, Mika Kojima, Shino Ohshima, Kazutaka Kitaura, Takaji Matsutani, Yoshinori Okada, Takashi Yahata, Ryoji Ito, Ikumi Katano, Hiroshi Suemizu, Ryuji Suzuki, Mamoru Ito, Sonoko Habu and Kiyoshi Ando, 2016 Clinical Research and Trials 2(3):164-173 doi: 10.15761/CRT.1000138 12. 霊長類胎盤の胎児/母体における免疫環境 木南理仁、亀谷美恵 2016 臨床免疫・アレルギー科 65(4):310-315

13. Identification of a CD4 variant in Microminipigs not detectable with available anti-CD4 monoclonal antibodies.
Tatsuya Matsubara, Naohito Nishii, Satoshi Takashima, Masaki Takasu, Noriaki Imaeda, Kayo Aiki-Oshimo, Kazuaki Yamazoe, Yoshie Kametani, Asako Ando, Hitoshi Kitagawa 2015 Veterinary immunology and Immunopathology 168(3-4):176-183

14. B cell Epitope-based Vaccination Therapy. Yoshie Kametani *, Asuka Miyamoto, Banri Tsuda, Yutaka Tokuda. 2015 Antibodies, 4(3), 225-239 doi:10.3390/antib4030225

15. Improved hematopoietic differentiation of primate embryonic stem cells by inhibition of the PI3K-AKT pathway under defined conditions.
Takenobu Nii, Tomotoshi Marumoto, Hiroshi Kohara, Saori Yamaguchi, Hirotaka Kawano, Erika Sasaki, Yoshie Kametani, Kenzaburo Tani. 2015 Exp Hematol 43:901-911 doi:10.1016/j.exphem.2015.06.001.

16. Common marmoset CD117-positive hematopoietic cells possess multipotency. Shin Shimada, Satoshi Nunomura, Shuya Mori, Hiroshi Suemizu, Toshio Itoh, Shuji Takabayashi, Yoshinori Okada, Takashi Yahata, Takashi Shiina, Hideki Katoh, Ryuji Suzuki, Kenzaburo Tani, Kiyoshi Ando, Hideo Yagita, Sonoko Habu, Erika Sasaki, Yoshie Kametani* 2015 Int Immunol 27:567-577

17. ヒト化NOGマウスにおける 抗体産生 B 細胞サフ?セット 宮本あすか、亀谷美恵 臨床免疫・アレルギー科 2015 63(3):278-283 (3月) 18. 免疫研究の霊長類モデルとしてのコモンマーモセット 布村聡、嶋田新、羅智靖、佐々木えりか、亀谷美恵 臨床免疫・アレルギー科 2015 63(1):78-83 (1月)

19. The Effect of Peptide Treatment on the HLA-Binding and Antibody Production in Peripheral Blood Mononuclear Cells Obtained from Japanese Breast Cancer Patients Banri Tsuda*, Yoshie Kametani, Asuka Miyamoto, Hirohito Miyako, Nobue Kumaki, Rin Ogiya, Risa Oshitanai, Mayako Terao, Toru Morioka, Naoki Niikura, Takuho Okamura, Yuki Saito, Yasuhiro Suzuki and Yutaka Tokuda Vaccines and Vaccination 2015 6:270.

20. Differentiation ability of multipotent hematopoietic stem/progenitor cells detected by a porcine specific anti-CD117 monoclonal antibody. Authors: Ohshima S, Mori S, Shigenari A, Miyamoto A, Takasu M, Imaeda N, Nunomura S, Okayama Y, Tanaka M, Kitagawa H, Kulski JK, Inoko H, Ando A, Kametani Y* BioScience Trends 2014 8:308-315 doi: 10.5582/bst.2014.01084

21. NKG2D functions as an activating receptor on natural killer cells in common marmoset (callithrix jacchus). Watanabe M, Kudo Y, Kawano M, Nakayama M, Nakamura K, Kameda M, Ebara M, Sato T, Nakamura M, Omine K, Kametani Y, Suzuki R, Ogasawara K. Int Immunol. 2014 26(11):597-606 doi: 10.1093/intimm/dxu053

22. Defect of tropomyosin-related kinase B isotype expression in ovarian clear cell adenocarcinoma. Goto Y, Kametani Y*, Kikugawa A, Tsuda B, Miyazawa M, Kajiwara H, Terao Y, Takekoshi S, Nakamura N, Takeda S, Mikami M BioScience Trends 2014 8:93-100  doi: 10.5582/bst.8.93

23. Genomic sequence analysis of the major histocompatibility complex (MHC) class I G/F segment in common marmoset (Callithrix jacchus). Kono A, Brameier M, Roos C, Suzuki S, Shigenari A, Kametani Y, Kitaura K, Suzuki R, Inoko H, Walter L, Shiina T J. Immunol. 2014 (April) 192(7):3239-3246  doi: 10.4049/jimmunol.1302745

24. エストロゲンと胎盤形成;新たな非ヒト霊長類コモンマーモセットを用いたヒト妊娠免疫モデルの提案 亀谷美恵、宮本あすか,石本人史、和泉俊一郎 比較内分泌学 2014 (1月) 40(151):11-13

25. 非ヒト霊長類コモンマーモセット免疫系の重度免疫不全マウスへの移植による再構築 亀谷美恵*、嶋田新、森修弥、佐々木えりか、安藤潔 2013 J.Germfree life and Gnotobiol 43(2):113-118

26. Immune-Related Gene Expression Profile in Laboratory Common Marmosets Assessed by an Accurate Quantitative Real-Time PCR Using Selected Reference Genes. Fujii Y., Kitaura K., Matsutani T., Shirai K., Suzuki S., Takasaki T., Kumagai K., Kametani Y., Shiina T., Takabayashi S., Katoh H., Hamada Y., Kurane I., Suzuki R. 2013 Pros ONE 8(2) e56296  doi: 10.1371/journal.pone.0056296

27. A human B cell receptor epitope-based erbB-2 peptide (N:163-182) with pan-reactivity to the T cells of Japanese breast cancer patients. Tsuda B, Kametani Y*, Goto Y, Saito Y, Suzuki Y, Habu S, Inoko H, Tokuda Y 2012 Vaccines and Vaccination, 3:7. Doi.org/10.4172/2157-7560.1000159

28. A new method for quantitative analysis of the T cell receptor V region repertoires in healthy common marmosets by microplate hybridization assay. Kitaura K, Fujii Y, Matsutani T, Shirai K, Suzuki S, Takasaki T, Shimada S, Kametani Y, Shiina T, Takabayashi S, Katoh H, Ogasawara K, Kurane I, Suzuki R.. J Immunol Methods 2012 384:81-91 (2)

29. Double expression of CD34 and CD117 on bone marrow progenitors is a hallmark of the development of functional mast cell of Calithrix Jucchus (common marmoset). Nunomura S, Shimada S, Kametani Y*, Yamada Y, Yoshioka M, Suemizu H, Ozawa M, Itoh T, Kono A, Suzuki R, Tani K, Ando K, Yagita H, Ra C, Habu S, Satake M, Sasaki E. Int. Immunol 2012 24:593-603  doi: 10.1093/intimm/dxs070

30. Porcine MHC classical class I genes are coordinately expressed in superantigen-activated mononuclear cells. Kametani Y, Ohshima S, Kita YF, Shimada S,  Kamiguchi H, Shiina T, Inoko H, Kulski JK and Ando A* Veterinary Immunology and Immunopathology 2012 148:252-259  doi: 10.1016/j.vetimm.2012.05.005.

31. Anti-tumor Effect of New HER2 Peptide Vaccination Based on B Cell Epitope. H. Miyako H, Kametani Y*, Katano I, Ito R, Tsuda B, Furukawa A, Saito Y, Ishikawa D, Ogino K, Sasaki S, Imai K, Habu S, Makuuchi H and Tokuda Y Anticancer Res 2011 31:3361-3368.

32. Effect of Liposome-Encapsulated Hemoglobin on Antigen-Presenting Cells in Mice. Kawaguchi AT, Aokawa, J, Yamada Y Yoshiba F, Kato S, Kametani Y, Artif Organs 2011 36:194-201

33. A novel ENU-induced mutation in Phospholipase C gamma 2 causes inflammatory arthritis, metabolic defects, and in vitro male infertility in the mouse. Abe K, Fuchs H, Boersma A, Hans W, Yu P, Kalaydjiev S, Klaften M, Adler T, Calzada-Wack J, Mossbrugger I, Rathkolb B, Rozman J, Prehn C, Maraslioglu M, Kametani Y, Shimada S, Adamski J, Busch DH, Esposito I, Klingenspor M, Wolf E, Wurst W, Gailus-Durner V, Katan M, Marschall S, Soewarto D, Wagner S, de Angelis MH. Arthritis Rheum. 2011 63:1301-11

34. IL-10産生CD4+ T 細胞について?コモンマーモセット免疫系の解析から: 亀谷美恵 臨床免疫・アレルギー科 54(4) 477-483 2010

35. ウイルス特異的メモリーT細胞の維持におけるプロバイオティクスの役割 石川裕樹、畑明宏、小林清志、相場勇志、清水恵子、亀谷美恵、田中和生、野田敏司 生物機能研究 14:16-23 2010

36. Protective potential of Bacillus coagulans, a spore-forming lactic acid bacterium, against cytomegalovirus infection. K.Shimizu,Y.Koga,Yuji Aiba,Kiyoshi Kobayashi,Akihiro Hata,Hiroki Ishikawa,Y.Kametani,Kazuo Tanaka, Shiro Ono S. Noda Report Jpn. Assoc. Biol. Func. Rec. 13:34-46 2010

37. サイトメガロウイルス感染症の検査と治療 野田 敏司、畑 明宏、石川 裕樹、前田 康行、志水 惠子、亀谷 美恵、伊東 秀記、田中 和生 生物機能研究会誌 12:1-9 2009

38. Analysis of hematopoietic progenitor cells of Common Marmoset.
Shimada S, Yamada Y, Suemizu H, Ito T, Satake M, Tani K, Sasaki E, Ito M, Habu S, Kametani Y Exp Animals 2010 59(3) Suppl: S59

39. Development of monoclonal antibodies for analyzing immune and hematopoietic systems of common marmoset.
Kametani Y, Suzuki D, Kohu K, Satake M, Suemizu H, Sasaki E, Ito T, Tamaoki N, Mizushima T, Ozawa M, Tani K, Kito M, Arai H, Koyanagi A, Yagita H, Habu S. Exp Hematol. 2009 37(11):1318-1329.

40. Effects of liposome-encapsulated hemoglobin on human immune system: evaluation in immunodeficient mice reconstituted with human cord blood stem cells. Kawaguchi AT, Kametani Y, Kato S, Furuya H, Tamaoki K, Habu S. Artif Organs. 2009 33(2):169-176.

41. Rapid histone deacetylation and transient HDAC association in the IL-2 promoter region of TSST-1-stimulated T cells. Kametani Y, Wang L, Koduka K, Sato T, Katano I, Habu S. Immunol Lett. 2008 119(1-2):97-102.

42. Comparison of 30 immunity-related genes from the common marmoset with orthologues from human and mouse.
Kohu K, Yamabe E, Matsuzawa A, Onda D, Suemizu H, Sasaki E, Tanioka Y, Yagita H, Suzuki D, Kametani Y, Takai T, Toyoda A, Habu S, Satake M. Tohoku J Exp Med. 2008 Jun;215(2):167-180.

43. Antigen-specific antibody production of human B cells in NOG mice reconstituted with the human immune system.
Ito R, Shiina M, Saito Y, Tokuda Y, Kametani Y, Habu S. Curr Top Microbiol Immunol. 2008  324:95-107. Review.

44. Development of human-human hybridoma from anti-Her-2 peptide-producing B cells in immunized NOG mouse.
Kametani Y, Shiina M, Katano I, Ito R, Ando K, Toyama K, Tsukamoto H, Matsumura T, Saito Y, Ishikawa D, Taki T, Ito M, Imai K, Tokuda Y, Kato S, Tamaoki N, Habu S. Exp Hematol. 2006 34(9):1240-1248.

45. エピトープペプチドワクチンの抗腫瘍効果ーアポトーシス誘導性抗erbB-2抗体CH401エピトープペプチドー三朝 博仁、亀谷 美恵、幕内 博康 2006 Surgery Frontier 13:40-43

46. T-cell specific enhancement of histone H3 acetylation in 5' flanking region of the IL-2 gene.
Wang L, Kametani Y, Katano I, Habu S. Biochem Biophys Res Commun. 2005 331(2):589-594.

47. Transient suppression of IgG1 with IL-6 over-expression in immunized TCR-transgenic mice.
Kametani Y, Katano I, Hirano Y, Mochida N, Takei E, Habu S. Immunol Lett. 2004 93(1):27-32.

48. ヒトにおけるT細胞の発達過程 亀谷 美恵、垣生 園子 2004 小児内科 36: 1691-1696

49. Functional CD5+ B cells develop predominantly in the spleen of NOD/SCID/gammac(null) (NOG) mice transplanted either with human umbilical cord blood, bone marrow, or mobilized peripheral blood CD34+ cells.
Matsumura T, Kametani Y, Ando K, Hirano Y, Katano I, Ito R, Shiina M, Tsukamoto H, Saito Y, Tokuda Y, Kato S, Ito M, Motoyoshi K, Habu S. Exp Hematol. 2003 31(9):789-797.

50. The in vivo development of human T cells from CD34(+) cells in the murine thymic environment.
Saito Y, Kametani Y, Hozumi K, Mochida N, Ando K, Ito M, Nomura T, Tokuda Y, Makuuchi H, Tajima T, Habu S. Int Immunol. 2002 14(10):1113-1124.

51. Reconstitution of functional human B lymphocytes in NOD/SCID mice engrafted with ex vivo expanded CD34(+) cord blood cells.
Li C, Ando K, Kametani Y, Oki M, Hagihara M, Shimamura K, Habu S, Kato S, Hotta T. Exp Hematol. 2002 30(9):1036-1043.

52. ヒト型免疫系再構築マウス 齋藤 雄紀、亀谷 美恵、垣生 園子 ヒト型モデル動物 pp 65-71

53. IL-7と自己反応性TCR重複トランスジェニックマウス(IL-7/2C)胸腺に検出されるB細胞の解析?自己免疫疾患における胸腺B細胞の機構解明のモデルとしてー
亀谷美恵、穂積勝人、渡辺守、日比紀文、西本宏史、垣生園子 Neuroimmunology 1999 7:128-129

54. 胸腺T細胞におけるPositive selectionとZAP-70 亀谷美恵、垣生園子 臨床免疫 1999 31:255-259

55. Ex vivo evidence for asymmetric tyrosine phosphorylation of ZAP-70 on double-positive thymocytes in the positive selection process.
Kametani Y, Goto H, Kobori A, Sato T, Ando K, Hozumi K, Nishimura T, Saito T, Yamamoto T, Habu S. Int Immunol. 1998 10(8):1203-1210.

56. Evidence for down-regulation of highly expressed TCR by CD4 and CD45 on non-selected CD4+CD8+ thymocytes.
Sato T, Hozumi K, Kishihara K, Kametani Y, Sato C, Kumagai Y, Mak TW, Habu S. Int Immunol. 1996 8(10):1529-1535.

57. Biochemical analysis of amyloid. Shinoda T, Takenawa T, Kametani Y.
Clin Dermatol. 1990 8(2):87-101..

58.βタンパク質サブペプチドに対するモノクローナル抗体による血清中交差性の検索
亀谷美恵、廣井哲也、竹縄辰行、篠田友孝、奥山典生、宮永和夫、飯沼和三 Dementia 1990 5:69-76

59. Preparation of a monoclonal antibody against a synthetic brain amyloid beta peptide (N1-10) and distribution of an immunoreactivity in serum. T. Shinoda, Y. Kametani, T. Hiroi, K. Iinuma, K. Miyanaga Amyloid and Amyloidosis. Edited by T. Isobe, S. Arai, F. Uchino, S. Kito, E. Tsubura Amyloid and Amyloidosis Plenum. New York. 1989 pp525-530

特許
出願番号 特願2015-004905 ブタ主要組織適合性抗原(MHC) SLA-1を特異的に認識するモノクローナル抗体 (2015/01/14)

1. Expression of glucocorticoid receptor shows negative correlation with human B-cell engraftment in PBMC-transplanted NOG-hIL-4-Tg mice. Toshiro Seki, Asuka Miyamoto, Shino Ohshima, Yusuke Ohno, Atsushi Yasuda, Yutaka Tokuda, Kiyoshi Ando, Yoshie Kametani*. BioScience Trends, in press (IF1.545)

2. Synthesis and Immunological Evaluation of Self-Adjuvanting Clustered N-Acetyl and N-Propionyl Sialyl-Tn Combined with A T-helper Cell Epitope as Antitumor Vaccine Candidates. Tsung-Che Chang, Yoshiyuki Manabe, Yukari Fujimoto, Shino Ohshima, Yoshie Kametani, Kazuya Kabayama, Yuka Nimura, Chun-Cheng Lin, Koichi Fukase* Angew Chem Int Ed Engl. in press (IF 11.994)

3.妊娠時の免疫寛容機構を解析するモデル動物としてのコモンマーモセットの有用性について 柏木寛史、亀谷美恵 先進生命科学研究所紀要2017 2:14-17

4. The significance of humanized mouse models for the evaluation of the humoral immune response against cancer vaccines. Review Yoshie Kametani*, Asuka Miyamoto, Toshiro Seki, Ryoji Ito, Sonoko Habu, Yutaka Tokuda Personalized Medicine Universe, 2018 in press